Carousel: Accelerating biomaterials R&D

Measure swelling, degradation, release and pH continuously on six samples at a time, around the clock, under controlled pH, temperature, strain and flow, for data closer to in vivo conditions.

21 CFR Part 11 compliant

ASTM/ISO-aligned methods

Carousel, model GC-01, with a clear lid over its sample chambers

Compatible form factors

  • Powders
  • Films and sheets
  • Tablets
  • Injectables
  • Microparticles
  • Amorphous gels
  • Foams
  • Implants

In a single Carousel run:

  • Swelling and hydration

    Mass at every timepoint, to 1 mg.

    • Gravimetric
    • Volumetric
    • Absorbency under load
    • Vapor transmission
  • Degradation

    Mass loss tracked for weeks to months.

    • Enzymatic
    • Accelerated
    • Hydrolytic
  • Release

    The medium is sampled automatically to UV-Vis, HPLC or LC-MS.

    • Drug
    • Extractables and leachables
    • UV-Vis, LC-MS, HPLC, ELISA
  • Computer vision

    On-board cameras capture each sample frame by frame.

    • Optical properties
    • Color
    • Transparency
    • Morphology
  • pH

    Monitored in line, from 1.5 to 12.

    • Monitored in line
    • pH 1.5 to 12
  • Mechanical properties

    • Stiffness
    • Mesh size
    • Crosslink density

    Method suitable for synthetic polymers only.

Manual testing versus Carousel

Free your time for discovery, let Carousel do the lifting.

Mass across one week

Illustrative · one sample, mass as % of its peak ± SD

Nights and weekend
MeasureManualCarouselResult
Testing hours a week 40 168 7x more data
Hands-on labor 5 hours 30 minutes 10x lower cost
Measurement error 10% 3% 3x lower variability
  • 7xMore data

    24/7 testing

    168 hours of testing a week instead of a 40-hour bench schedule.

  • 10xLower cost

    Fully automated

    Labor and consumable costs per datapoint, up to 10x lower.

  • 3xHigher precision

    Filtration conditioning

    Lower sample-to-sample variability than manual gravimetric methods.

Technical specifications

Check Carousel against your test plan with the full specifications.

Carousel GC-01Technical data sheet
Measurement
Maximum load100 g
Gravimetric resolution1 mg
Minimum sample mass (dry)5 mg
Chamber and fluidics
Chamber volume24 mL
Mechanical pressure0.1 to 1 PSI
Filter pore sizes0.45, 50, 100, 200 and 1,000 µm
Filter materialsPolypropylene, nylon, PTFE
Flow control5 to 150 mL/min
Environment
Temperature controlAmbient to 60 °C
pH compatibility and monitoring1.5 to 12
System
Dimensions400 mm wide, 600 mm high, 400 mm deep
Sample form factorsLiquids, gels (semi-solids), solids
ModalityOnline (cloud) or offline
Data output.csv and .jpg

Specifications are subject to change. Custom configurations are available on request.

Bring Carousel into your lab, or run with ours

  • Buy or lease

    Carousel in your lab, with install, training, verification and validation (V&V) and a 30-day trial.

    Configure a Carousel
  • Run remotely

    Send samples and run your study on our units, or have our lab run it for you.

    See R&D services
A row of palm trees against a blue sky

Try Carousel on your material

Tell us what you're developing. We'll scope a trial, a lease or a study, and the first consultation is on us.

By sending, you agree to our terms and privacy policy. Please leave out confidential formulation details until an NDA is in place.